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Anne-Kathrin Classen Profile Page
Anne-Kathrin Classen

Contact

Lab: Prof. Dr. Anne-Kathrin Classen
Department: Heisenberg Research Group Leader
Address: HMH, Habsburgerstr. 49
79104 Freiburg
Phone: +49 761 203 97109
E-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Lab homepage: classenlab.net/
PhD positions available: YES
Research Area: Developmental Biology
Research Interests: - Signalling and proliferation during regeneration
- Epithelial architecture and biomechanics
- Cell competition

CV

Education & Training: 2002-2006: PhD in Biology, Max Planck Institute of Molecular Cell Biology and Genetics and Technical University Dresden, Germany.
2000-2002: Master of Science (MSc) in Biomolecular Sciences, The University of Amsterdam, Netherlands.
1997-2000: Bachelor of Science (BSc) in Cell Biology, The University of Manchester, UK.
Employment & Experience: since 2011: Research Group Leader, Faculty of Biology, University of Freiburg, Germany
2011-2016: Emmy Noether Research Group Leader, Faculty of Biology, Ludwig-Maximilians-University, Munich, Germany
2006-2011: Postdoctoral fellow, University of California at Berkeley, USA

Honors

Honors and Awards:

2020: Heisenberg Program Fellowship, Deutsche Forschungsgemeinschaft, Germany.
2017: Boehringer Ingelheim Plus3 Programme Fellowship
2012: ‘CAS Young Centre’ Membership, Center of Advanced Studies, Ludwig-Maximilians-University, Germany.
2011: Emmy Noether Programme Fellowship, Deutsche Forschungsgemeinschaft, Germany.
2007: JCCMF Postdoctoral Fellowship, Jane Coffin Childs Memorial Fund for Medical Research, New Haven (Yale), USA.
2007: MSc thesis material stipendFreundeskreis e.V of the Max-Delbrück-Center of Molecular Medicine, Berlin, Germany.
2000: Jencons Prize, Honours School of Cell Biology, University of Manchester, UK.

Publications

Selected Publications:

Balaji R, Weichselberger V, Classen AK. Response of Drosophila epithelial cell and tissue shape to external forces in vivo. Development. 2019 Sep 6;146(17):dev171256.  Abstract

Cosolo A, Jaiswal J, Csordás G, Grass I, Uhlirova M, Classen AK. JNK-dependent cell cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress. Elife. 2019 Feb 8;8:e41036.  Abstract

La Fortezza M, Grigolon G, Cosolo A, Pindyurin A, Breimann L, Blum H, van Steensel B, Classen AK. DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis. Epigenetics Chromatin. 2018 Jun 5;11(1):27.  Abstract

Balaji R, Bielmeier C, Harz H, Bates J, Stadler C, Hildebrand A, Classen AK. Calcium spikes, waves and oscillations in a large, patterned epithelial tissue. Sci Rep. 2017 Feb 20;7:42786.  Abstract

La Fortezza M, Schenk M, Cosolo A, Kolybaba A, Grass I, Classen AK. JAK/STAT signalling mediates cell survival in response to tissue stress. Development. 2016 Aug 15;143(16):2907-19.  Abstract

Bielmeier C, Alt S, Weichselberger V, La Fortezza M, Harz H, Jülicher F, Salbreux G, Classen AK. Interface Contractility between Differently Fated Cells Drives Cell Elimination and Cyst Formation. Curr Biol. 2016 Mar 7;26(5):563-74.  Abstract

Bunker BD, Nellimoottil TT, Boileau RM, Classen AK, Bilder D. The transcriptional response to tumorigenic polarity loss in Drosophila. Elife. 2015 Feb 26;4.  Abstract

Classen AK, Bunker BD, Harvey KF, Vaccari T, Bilder D. A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling. Nat Genet. 2009 Oct;41(10):1150-5.  Abstract

Kolahi KS, White PF, Shreter DM, Classen AK, Bilder D, Mofrad MR. Quantitative analysis of epithelial morphogenesis in Drosophila oogenesis: New insights based on morphometric analysis and mechanical modeling. Dev Biol. 2009 Jul 15;331(2):129-39.  Abstract

Classen AK, Anderson KI, Marois E, Eaton S. Hexagonal packing of Drosophila wing epithelial cells by the planar cell polarity pathway. Dev Cell. 2005 Dec;9(6):805-17.  Abstract

SGBM PhD students

SGBM PhD students:

Track 1

Deepti Prasad (since January 2018)

Track 2

Janhvi Jaiswal (since September 2016)

 

Alumni

Vanessa Weichselberger (May 2016-May 2022)

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