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Contact
| Lab: | Prof. Dr. Bernd Kammerer |
| Department: | ZBSA - Metabolomics |
| Address: | Habsburgerstr. 49 79104 Freiburg |
| Phone: | +49 (0)761 203 97137 |
| E-mail: | This e-mail address is being protected from spambots. You need JavaScript enabled to view it |
| Lab homepage: | www.zbsa.uni-freiburg.de/core_fac/Metabolomics |
| PhD positions available: | YES |
| Research Area: | Molecular Medicine |
| Research Interests: | • Regulation of plant biochemical pathways to investigate central metabolism, biosynthesis of secondary metabolites, signalling and stress response • Biosynthesis and analysis of secondary metabolites from different bacterial strains as new therapeutic agents by „combinatorial biosynthesis” • Metabolomics to unravel molecular mechanisms involved in Parkinson's disease • Biomarker identification in breast cancer • Metabolomics Changes in Ciliopathy: The role of the nephronophthisis Anks6 module in development and tissue homeostasis • Analysis of the mitochondrial metabolome smORF gene mutants in yeast • Metabolomic signatures of aggressive prostate cancer |
CV
| Education & Training: | 1997 Doctoral Thesis, Institute of Organic Chemistry, University of Tübingen, Germany |
| Employment & Experience: | 2012 Venia Legendi for ”Medical Bioanalytics”, Faculty of Medicine, University of Freiburg, Germany Since 2010 Head of Core Facility Metabolomics and Group Leader, Center for Biosystems Analysis ZBSA, Albert-Ludwigs-University Freiburg, Germany 2008 Habilitation at Institute of Medical Chemistry, University of Tübingen, Germany Venia Legendi for “Pharmaceutical Analytics”, Faculty of Chemistry and Pharmacy, University of Tübingen, Germany 2001 - 2010 Laboratory Head and Group Leader at Institute of Pharmacology and Toxicology, Department of Clinical Pharmacology at University Hospital Tübingen, Germany 2000 – 2001 Laboratory Head Mass Spectrometry at University of Tübingen, Germany 1998 – 1999 Postdoctoral Position at Novartis Pharma AG, Basel, Switzerland 1997 – 1998 Scientific Assistant at Institute of Organic Chemistry, University of Tübingen, Germany |
Publications
| Selected Publications: | Willmann, Lucas; Erbes, Thalia; Halbach, Sebastian; Brummer, Tilman; Jaeger, Markus; Hirschfeld, Marc; Fehm, Tanja; Neubauer, Hans; Stickeler, Elmar; Kammerer, Bernd: “Exometabolom analysis of breast cancer cell lines: Metabolic signature”, Scientific Reports (2015), 5, 13374. Abstract Willmann, Lucas; Erbes, Thalia; Krieger, Sonja; Trafkowski, Jens; Rodamer, Michael; Kammerer, Bernd: „Metabolome analysis via comprehensive two-dimensional liquid chromatography: identification of modified nucleosides from RNA metabolism”, Analytical and Bioanalytical Chemistry (2015), 407(13), 3555-3566. Abstract Jaeger C, Tellström V, Zurek G, König G, Eimer S, Kammerer B: “Metabolomic changes in Caenorhabditis elegans lifespan mutants as evident from GC–EI–MS and GC–APCI–TOF–MS profiling”, Metabolomics (2014), 10(5), 859-876. Abstract Teperino R, Amann S, Bayer M, McGee SL, Loipetzberger A, Connor T, Jaeger C, Kammerer B, Winter L, Wiche G, Dalgaard K, Selvaraj M, Gaster M, Lee-Young RS, Febbraio MA, Knauf C, Cani PD, Aberger F, Penninger JM, Pospisilik JA, Esterbauer H: “Hedgehog Partial Agonism Drives Warburg-like Metabolism in Muscle and Brown Fat”, Cell 2012, 151(2):414-26. Abstract Martin Michaelis, Florian Rothweiler, Denise Klassert, Andreas von Deimling, Kristoffer Weber, Boris Fehse, Bernd Kammerer, Hans Wilhelm Doerr, Jindrich Cinatl jr: “Reversal of P-glycoprotein-mediated multi-drug resistance by the MDM2 antagonist nutlin-3“, Cancer Research (2009), 69(2), 416-421. Abstract Antje Frickenschmidt, Holger Fröhlich, Andreas Zell, Stefan Laufer, Christoph H. Gleiter, Hartmut Liebich and Bernd Kammerer: “Metabonomics in cancer diagnosis: Mass spectrometry based profiling of urinary nucleosides from breast cancer patients”, Biomarkers (2008), 13(4), 435-449. Abstract Bernd Kammerer, Holger Scheible, Gabriela Zurek, Markus Godejohann, Klaus-Peter Zeller, Christoph H. Gleiter, Wolfgang Albrecht and Stefan Laufer: “In vitro metabolite identification of ML3403, a 4-pyridinylimidazole-type p38 MAP kinase inhibitor by LC-Qq-TOF-MS and LC-SPE-cryo-NMR/MS”, Xenobiotica (2007), 37(3), 280-297. Abstract Dino Bullinger, Hans Neubauer, Tanja Fehm, Stefan Laufer, Christoph H. Gleiter and Bernd Kammerer: „Metabolic signature of breast cancer cell line MCF-7: Profiling of modified nucleosides via LC-IT MS coupling”, BMC Biochemistry (2007), 8(25) 1-14. Abstract Kammerer, Bernd; Frickenschmidt, Antje; Laufer, Stefan; Gleiter, Christoph H. and Liebich, Hartmut: „MALDI-TOFMS Analysis of Urinary Nucleosides”, Journal of the American Society for Mass Spectrometry (2005), 16(6), 940-947. Abstract Kammerer, Bernd; Kahlich, Rainer; Laufer, Stefan; Li, Shuming; Heide, Lutz and Gleiter, Christoph H.: “Mass Spectrometric pathway monitoring of secondary metabolites - Systematic analysis of culture extracts of Streptomyces species”, Analytical Biochemistry (2004), 335, 17-29. Abstract |
SGBM PhD students
| SGBM PhD students: |
Alumni: Simon Lagies (April 2017-January 2021) Manuel Schlimpert (October 2015-February 2019) |
