Bernd Kammerer

Bernd Kammerer Profile Page

Contact

Lab:	Prof. Dr. Bernd Kammerer
Department:	Hilde-Mangold-Haus HMH
Address:	Habsburgerstr. 49 79104 Freiburg
Phone:	+49 (0)761 203 97137
E-mail:	This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Lab homepage:	www.metabolomics.uni-freiburg.de/
PhD positions available:	YES
Research Area:	Molecular Medicine
Research Interests:	• Regulation of plant biochemical pathways to investigate central metabolism, biosynthesis of secondary metabolites, signalling and stress response • Biosynthesis and analysis of secondary metabolites from different bacterial strains as new therapeutic agents by „combinatorial biosynthesis” • Metabolomics to unravel molecular mechanisms involved in Parkinson's disease • Biomarker identification in breast cancer • Metabolomics Changes in Ciliopathy: The role of the nephronophthisis Anks6 module in development and tissue homeostasis • Analysis of the mitochondrial metabolome smORF gene mutants in yeast • Metabolomic signatures of aggressive prostate cancer

CV

Education & Training:

1997 Doctoral Thesis, Institute of Organic Chemistry, University of Tübingen, Germany

Employment & Experience:

2012 Venia Legendi for ”Medical Bioanalytics”, Faculty of Medicine, University of Freiburg, Germany
Since 2010 Head of Core Facility Metabolomics and Group Leader, Center for Biosystems Analysis ZBSA, Albert-Ludwigs-University Freiburg, Germany
2008 Habilitation at Institute of Medical Chemistry, University of Tübingen, Germany
Venia Legendi for “Pharmaceutical Analytics”, Faculty of Chemistry and Pharmacy, University of Tübingen, Germany
2001 - 2010 Laboratory Head and Group Leader at Institute of Pharmacology and Toxicology, Department of Clinical Pharmacology at University Hospital Tübingen, Germany
2000 – 2001 Laboratory Head Mass Spectrometry at University of Tübingen, Germany
1998 – 1999 Postdoctoral Position at Novartis Pharma AG, Basel, Switzerland
1997 – 1998 Scientific Assistant at Institute of Organic Chemistry, University of Tübingen, Germany

Publications

Selected Publications:

Lagies S, Pichler R, Vladimirov G, Gawron J, Bäzner F, Schreiner A, Kadena D, Plattner DA, Lienkamp SS, Kammerer B. Metabolic and Lipidomic Assessment of Kidney Cells Exposed to Nephrotoxic Vancomycin Dosages. Int J Mol Sci. 2021 Sep 18;22(18):10111. Abstract

Bauer C, Quante M, Breunis WB, Regina C, Schneider M, Andrieux G, Gorka O, Groß O, Boerries M, Kammerer B, Hettmer S. Lack of Electron Acceptors Contributes to Redox Stress and Growth Arrest in Asparagine-Starved Sarcoma Cells. Cancers (Basel). 2021 Jan 22;13(3):412. Abstract

Frensch B, Lechtenberg T, Kather M, Yunt Z, Betschart M, Kammerer B, Lüdeke S, Müller M, Piel J, Teufel R. Enzymatic spiroketal formation via oxidative rearrangement of pentangular polyketides. Nat Commun. 2021 Mar 4;12(1):1431. Abstract

Braun LM, Lagies S, Guenzle J, Fichtner-Feigl S, Wittel UA, Kammerer B. Metabolic Adaptation during nab-Paclitaxel Resistance in Pancreatic Cancer Cell Lines. Cells. 2020 May 19;9(5):1251. Abstract

Pan D, Wiedemann N, Kammerer B. Heat Stress-Induced Metabolic Remodeling in Saccharomyces cerevisiae. Metabolites. 2019 Nov 5;9(11):266. Abstract

Lagies S, Pichler R, Bork T, Kaminski MM, Troendle K, Zimmermann S, Huber TB, Walz G, Lienkamp SS, Kammerer B. Impact of Diabetic Stress Conditions on Renal Cell Metabolome. Cells. 2019 Sep 24;8(10):1141. Abstract

Willmann L, Erbes T, Halbach S, Brummer T, Jäger M, Hirschfeld M, Fehm T, Neubauer H, Stickeler E, Kammerer B. Exometabolom analysis of breast cancer cell lines: Metabolic signature. Sci Rep. 2015 Aug 21;5:13374. Abstract

Willmann L, Erbes T, Krieger S, Trafkowski J, Rodamer M, Kammerer B. Metabolome analysis via comprehensive two-dimensional liquid chromatography: identification of modified nucleosides from RNA metabolism. Anal Bioanal Chem. 2015 May;407(13):3555-66. Abstract

Jaeger, C., Tellström, V., Zurek, G. et al. Metabolomic changes in Caenorhabditis elegans lifespan mutants as evident from GC–EI–MS and GC–APCI–TOF–MS profiling. Metabolomics 10, 859–876 (2014). Article

Teperino R, Amann S, Bayer M, McGee SL, Loipetzberger A, Connor T, Jaeger C, Kammerer B, Winter L, Wiche G, Dalgaard K, Selvaraj M, Gaster M, Lee-Young RS, Febbraio MA, Knauf C, Cani PD, Aberger F, Penninger JM, Pospisilik JA, Esterbauer H. Hedgehog partial agonism drives Warburg-like metabolism in muscle and brown fat. Cell. 2012 Oct 12;151(2):414-26. Abstract

SGBM PhD students

SGBM PhD students:

Alumni:

Simon Lagies (April 2017-January 2021)

Manuel Schlimpert (October 2015-February 2019)